North American serum, typically referring to North American Fetal Bovine Serum (FBS), is derived from fetal cows in regions such as the United States and Canada. It is commonly used in cell culture to provide essential nutrients, growth factors, and hormones that support cell growth and maintenance. North American FBS is widely used in research and biotechnology, although it may carry a relatively higher risk of certain contaminants compared to serum sourced from other regions.